Europe take rheumatic drug Sarilumab (Kevzara) in battle against Covid 19

Okay friends, a glimmer of hope on the horizon. In the past weeks I have reported reported that our beloved Kevzara would be an ideal drug against for Covid 19. The whole thing continues to develop.

Denmark also reports about it, and yes it would be fantastic if this expensive drug really helps.

How does Kevzara work
The active substance in Kevzara, sarilumab, is a monoclonal antibody (a type of protein) that has been designed to bind to and block the receptor (target) for a molecule called interleukin-6. Interleukin-6 is involved in inflammatory processes and is present in high concentrations in the joints of patients with rheumatoid arthritis. By preventing interleukin-6 from binding to its receptors, sarilumab reduces inflammation and other symptoms associated with rheumatoid arthritis.

Hur man undviker hudreaktioner med Kevzara

Do not forget. This does not mean that we are immune to Covid 19. Because our immune system is incorrectly clocked, we react differently.

Sanofi-aventis annonser första patient utanför USA fick behandling med Kevzara® (sarilumab)

Phase 2/3 trial initiated in Italy, Spain, Germany, France, Canada and Russia and is enrolling patients immediately
Kevzara inhibits IL-6, which may play a role in driving the inflammatory immune response that causes acute respiratory distress syndrome observed in patients with severe COVID-19 infection
Sanofi is leading trials outside the U.S., while Regeneron is leading U.S. trials

Kevzara is a fully-human monoclonal antibody that inhibits the interleukin-6 (IL-6) pathway by binding and blocking the IL-6 receptor. IL-6 may play a role in driving the overactive inflammatory response in the lungs of patients who are severely or critically ill with COVID-19 infection. The role of IL-6 is supported by preliminary data from a single-arm study in China using another IL-6 receptor inhibitor

Läs mer Sanofi

NCT04315298

Kevzara är används mot svårt reumatoid artrit som en enda terapi eller tillsammans med MTX